onshore

R&D and flex space for lease in San Francisco

Industrial leasing guide

Onshore has 23 current R&D and flex listings in San Francisco. Each card shows the published size and asking rent where available, and links to the full listing with photos and unit details. Updated 2026-10-01.

Suite 100 reception and lounge
Potrero Hill

Suite 100 reception and lounge

555 De Haro St

8,196 SF · $34,150/mo · computed

Suite 100 · ground-floor flex

Suite 3D · warehouse / flex
Bayview · 2 spaces

Suite 3D · warehouse / flex

3450 3rd St

750–3,150 SF · Rent upon request

Suite 3D · Bayview

Existing interior · renovation underway
SoMa · 2 spaces

Existing interior · renovation underway

732 Brannan St

8,735–8,760 SF · Rent upon request

SoMa · two floors / full building

560 4th St view 1
SoMa

560 4th St

5,000 SF · Rent upon request

SoMa / South Beach

55 Potrero Ave view 1
Potrero Hill

55 Potrero Ave

≈ 10,000 SF · Rent upon request

Showplace Square / Potrero Hill

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19 Heron St view 1
SoMa · 2 spaces

19 Heron St

6,400 SF · $15,000/mo · computed

SoMa / West SoMa

230-236 8th St view 1
SoMa · 2 spaces

230-236 8th St

5,243 SF · Rent upon request

SoMa / West SoMa

42 Dore St view 1
SoMa

42 Dore St

3,900 SF · $15,925/mo · computed

SoMa / West SoMa

146 11th St view 1
SoMa · 2 spaces

146 11th St

3,600 SF · Rent upon request

SoMa / West SoMa

2122 Bryant St view 1
Mission

2122 Bryant St

2,500 SF · Rent upon request

Mission / Inner Mission

724 Valencia St view 1
Mission

724 Valencia St

2,619 SF · $11,998/mo · computed

Mission / Mission Dolores

Building shell interior · floor not identified in brochure
Design District

Building shell interior · floor not identified in brochure

300 Kansas St · Level 6

10,681 RSF · Rent upon request

Design District · R&D shell and rooftop

R&D / lab interior
South Beach

R&D / lab interior

390 Fremont St

9,150 SF · $53,375/mo · computed

600A · 3-phase · 490 V · full building

Shared ground-floor lobby
Mission Bay · 3 spaces

Shared ground-floor lobby

1700 Owens St

4,738–7,127 SF · From $45,406/mo · computed

5th floor · Suites 500 + 540

665 3rd St view 1
SoMa · 4 spaces

665 3rd St

2,200–3,958 SF · $4,950–$10,885/mo · computed

South Beach / Oracle Park

Other space in San Francisco

R&D and flex space in other areas

Sam, your Onshore broker

Want to see more places like these?

Tell me what your team needs. I’ll help you find the right fit.

Set up a call